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STAT3 單克隆抗體

貨號(hào) 品牌 CAS 規(guī)格 銷售價(jià)(RMB) 折扣價(jià)(RMB) 備注 數(shù)量
ABM0067-100μL Abbkine 無(wú) 100μL 1998 1998 無(wú)
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商品信息

產(chǎn)品英文名稱STAT3 Monoclonal Antibody
免疫原重組蛋白
宿主小鼠
反應(yīng)性人, 大鼠, 小鼠
應(yīng)用IHC-P, WB
實(shí)驗(yàn)建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:1000-1:2000，IHC-P：1:100-1:200。
克隆性單克隆
純化工藝使用表位特異性的免疫原，通過親和層析，從小鼠腹水中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
分子量79, 86 KD
儲(chǔ)存緩沖液PBS緩沖液（pH 7.4），含有0.5%BSA（穩(wěn)定劑），0.02％疊氮化鈉（防腐劑）和50％甘油。
保存建議自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件藍(lán)冰運(yùn)輸
警告本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。

附加信息

背景The protein encoded by STAT3 (signal transducer and activator of transcription 3) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in STAT3 are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
基因ID6774
別名STAT3; APRF; Signal transducer and activator of transcription 3; Acute-phase response factor
蛋白質(zhì)IDP40763