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JNK1/2/3 (磷酸化-Thr183)多克隆抗體

貨號 品牌 CAS 規(guī)格 銷售價(RMB) 折扣價(RMB) 備注 數(shù)量
ABP0041-100μL Abbkine 100μL 1998 1998
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商品信息

產(chǎn)品英文名稱JNK1/2/3 (phospho Thr183) Polyclonal Antibody
免疫原合成多肽:人源JNK1/2/3 磷酸化位點為中心:T183
宿主
反應性人, 大鼠, 小鼠
應用ELISA, IF, IHC-P, WB
實驗建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:5000。
克隆性多克隆
純化工藝使用表位特異性的免疫原,通過親和層析,從兔抗血清中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
分子量54 KD
儲存緩沖液PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。
保存建議自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。
運輸條件藍冰運輸
警告本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權或其他違規(guī)行為,我們不承擔任何責任。

附加信息

背景Mitogen-activated protein kinase 8 encoded by MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Mitogen-activated protein kinase 8 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. Mitogen-activated protein kinase 8 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of MAPK8 suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported.
基因ID5599/5601/5602
別名MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi
其它該抗體可檢測內源蛋白
蛋白質IDP45983/P45984/P53779