貨號 | 品牌 | CAS | 規(guī)格 | 銷售價(RMB) | 折扣價(RMB) | 備注 | 數(shù)量 |
ABP0041-100μL | Abbkine | 無 | 100μL | 1998 | 1998 | 無 |
產(chǎn)品英文名稱 | JNK1/2/3 (phospho Thr183) Polyclonal Antibody |
免疫原 | 合成多肽:人源JNK1/2/3 磷酸化位點為中心:T183 |
宿主 | 兔 |
反應性 | 人, 大鼠, 小鼠 |
應用 | ELISA, IF, IHC-P, WB |
實驗建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:5000。 |
克隆性 | 多克隆 |
純化工藝 | 使用表位特異性的免疫原,通過親和層析,從兔抗血清中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
分子量 | 54 KD |
儲存緩沖液 | PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復凍融。 |
運輸條件 | 藍冰運輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權或其他違規(guī)行為,我們不承擔任何責任。 |
背景 | Mitogen-activated protein kinase 8 encoded by MAPK8 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Mitogen-activated protein kinase 8 is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. Mitogen-activated protein kinase 8 is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of MAPK8 suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Several alternatively spliced transcript variants encoding distinct isoforms have been reported. |
基因ID | 5599/5601/5602 |
別名 | MAPK8; JNK1; PRKM8; SAPK1; SAPK1C; Mitogen-activated protein kinase 8; MAP kinase 8; MAPK 8; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1; MAPK9; JNK2; PRKM9; SAPK1A; Mi |
其它 | 該抗體可檢測內源蛋白 |
蛋白質ID | P45983/P45984/P53779 |
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