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貨號(hào) | 品牌 | CAS | 規(guī)格 | 銷售價(jià)(RMB) | 折扣價(jià)(RMB) | 備注 | 數(shù)量 |
ABP0047-100μL | Abbkine | 無(wú) | 100μL | 1998 | 1998 | 無(wú) |
產(chǎn)品英文名稱 | p38 (phospho Thr180/Y182) Polyclonal Antibody |
免疫原 | 合成多肽:人源p38 磷酸化位點(diǎn)為中心:T180/Y182 |
宿主 | 兔 |
反應(yīng)性 | 人, 大鼠, 小鼠, 豚鼠 |
應(yīng)用 | ELISA, IF, IHC-P, WB |
實(shí)驗(yàn)建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:50-1:200,IHC-P:1:100-1:300,ELISA:1:5000。 |
克隆性 | 多克隆 |
純化工藝 | 使用表位特異性的免疫原,通過(guò)親和層析,從兔抗血清中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
分子量 | 38 KD |
儲(chǔ)存緩沖液 | PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。 |
運(yùn)輸條件 | 藍(lán)冰運(yùn)輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。 |
背景 | Mitogen-activated protein kinase 14 encoded by MAPK14 is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Mitogen-activated protein kinase 14 is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs, or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with mitogen-activated protein kinase 14.The substrates of mitogen-activated protein kinase 14 include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of mitogen-activated protein kinase 14 in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of MAPK14 encoding distinct isoforms have been reported. |
基因ID | 1432 |
別名 | MAPK14; CSBP; CSBP1; CSBP2; CSPB1; MXI2; SAPK2A; Mitogen-activated protein kinase 14; MAP kinase 14; MAPK 14; Cytokine suppressive anti-inflammatory drug-binding protein; CSAID-binding protein; CSBP; MAP kinase MXI2; MAX-interacting protein |
其它 | 該抗體可檢測(cè)內(nèi)源蛋白 |
蛋白質(zhì)ID | Q16539 |
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