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E-cadherin多克隆抗體

貨號(hào) 品牌 CAS 規(guī)格 銷售價(jià)(RMB) 折扣價(jià)(RMB) 備注 數(shù)量
ABP0083-100μL Abbkine 100μL 1998 1998
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商品信息

產(chǎn)品英文名稱E-cadherin Polyclonal Antibody
免疫原合成多肽:人源蛋白的C末端,E-cadherin,AA:810-890
宿主
反應(yīng)性人, 大鼠, 小鼠
應(yīng)用ELISA, IF, IHC-P, WB
實(shí)驗(yàn)建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:20000。
克隆性多克隆
純化工藝使用表位特異性的免疫原,通過親和層析,從兔抗血清中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
分子量125-130 KD
儲(chǔ)存緩沖液PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。
保存建議自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件藍(lán)冰運(yùn)輸
警告本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。

附加信息

背景CDH1 encodes a classical cadherin of the cadherin superfamily. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature glycoprotein. This calcium-dependent cell-cell adhesion protein is comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in CDH1 are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function of this gene is thought to contribute to cancer progression by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. CDH1 is present in a gene cluster with other members of the cadherin family on chromosome 16.
基因ID999/1000/1001/1002
別名CDH1; CDHE; UVO; Cadherin-1; CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD antigen CD324; CDH2; CDHN; NCAD; Cadherin-2; CDw325; Neural cadherin; N-cadherin; CD antigen CD325; CDH3; CDHP; Cadherin-3; Placental cadherin; P-cadhe
其它該抗體可檢測內(nèi)源蛋白
蛋白質(zhì)IDP12830/P19022/P22223/P55283