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MMP-2多克隆抗體

貨號(hào) 品牌 CAS 規(guī)格 銷售價(jià)(RMB) 折扣價(jià)(RMB) 備注 數(shù)量
ABP0101-100μL Abbkine 無(wú) 100μL 1998 1998 無(wú)
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商品信息

產(chǎn)品英文名稱MMP-2 Polyclonal Antibody
免疫原合成多肽:人源蛋白的C末端,MMP-2,AA:580-660
宿主
反應(yīng)性人, 大鼠, 小鼠, 猴
應(yīng)用ELISA, IF, IHC-P, WB
實(shí)驗(yàn)建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IF:1:200-1:1000,IHC-P:1:100-1:300,ELISA:1:20000。
克隆性多克隆
純化工藝使用表位特異性的免疫原,通過(guò)親和層析,從兔抗血清中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
分子量74 KD
儲(chǔ)存緩沖液PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。
保存建議自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件藍(lán)冰運(yùn)輸
警告本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。

附加信息

背景MMP2 is a member of the matrix metalloproteinase (MMP) gene family, that are zinc-dependent enzymes capable of cleaving components of the extracellular matrix and molecules involved in signal transduction. 72 kDa type IV collagenase encoded by MMP2 is a gelatinase A, type IV collagenase, that contains three fibronectin type II repeats in its catalytic site that allow binding of denatured type IV and V collagen and elastin. Unlike most MMP family members, activation of this protein can occur on the cell membrane. This enzyme can be activated extracellularly by proteases, or, intracellulary by its S-glutathiolation with no requirement for proteolytical removal of the pro-domain. This protein is thought to be involved in multiple pathways including roles in the nervous system, endometrial menstrual breakdown, regulation of vascularization, and metastasis. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
基因ID4313
別名MMP2; CLG4A; 72 kDa type IV collagenase; 72 kDa gelatinase; Gelatinase A; Matrix metalloproteinase-2; MMP-2; TBE-1
其它該抗體可檢測(cè)內(nèi)源蛋白
蛋白質(zhì)IDP08253