貨號 | 品牌 | CAS | 規(guī)格 | 銷售價(RMB) | 折扣價(RMB) | 備注 | 數(shù)量 |
ABP0104-100μL | Abbkine | 無 | 100μL | 1998 | 1998 | 無 |
產(chǎn)品英文名稱 | N/H/K-Ras Polyclonal Antibody |
免疫原 | 合成多肽:人源蛋白的N末端,N/H/K-Ras,AA:10-90 |
宿主 | 兔 |
反應(yīng)性 | 人, 大鼠, 小鼠 |
應(yīng)用 | ELISA, IHC-P, WB |
實驗建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:500-1:2000,IHC-P:1:100-1:300,ELISA:1:20000。 |
克隆性 | 多克隆 |
純化工藝 | 使用表位特異性的免疫原,通過親和層析,從兔抗血清中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
分子量 | 21 KD |
儲存緩沖液 | PBS緩沖液(pH 7.4),含有0.5%BSA(穩(wěn)定劑),0.02%疊氮化鈉(防腐劑)和50%甘油。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。 |
運輸條件 | 藍冰運輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔任何責(zé)任。 |
背景 | HRAS belongs to the Ras oncogene family, whose members are related to the transforming genes of mammalian sarcoma retroviruses. The products encoded by these genes function in signal transduction pathways. These proteins can bind GTP and GDP, and they have intrinsic GTPase activity. GTPase Hras undergoes a continuous cycle of de- and re-palmitoylation, which regulates its rapid exchange between the plasma membrane and the Golgi apparatus. Mutations in this gene cause Costello syndrome, a disease characterized by increased growth at the prenatal stage, growth deficiency at the postnatal stage, predisposition to tumor formation, mental retardation, skin and musculoskeletal abnormalities, distinctive facial appearance and cardiovascular abnormalities. Defects in this gene are implicated in a variety of cancers, including bladder cancer, follicular thyroid cancer, and oral squamous cell carcinoma. Multiple transcript variants, which encode different isoforms, have been identified for this gene. |
基因ID | 3265/3845/4893 |
別名 | NRAS; HRAS1; GTPase NRas; Transforming protein N-Ras; HRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; KRAS; KRAS2; RASK2; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras |
其它 | 該抗體可檢測內(nèi)源蛋白 |
蛋白質(zhì)ID | P01111/P01112/P01116 |
全國免費熱線:400-6700-360
閩ICP備19023500號
閩公網(wǎng)安備 35010202001014號