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貨號(hào) | 品牌 | CAS | 規(guī)格 | 銷售價(jià)(RMB) | 折扣價(jià)(RMB) | 備注 | 數(shù)量 |
ABM40200-100 μL | Abbkine | 無(wú) | 100μL | 1616 | 1616 | 無(wú) | |
ABM40200-30μL | Abbkine | 無(wú) | 30μL | 739 | 739 | 無(wú) | |
ABM40200-100μL | Abbkine | 無(wú) | 100μL | 1616 | 1616 | 無(wú) |
產(chǎn)品英文名稱 | Acetyl Lysine Monoclonal Antibody |
免疫原 | 純化蛋白 |
宿主 | 小鼠 |
反應(yīng)性 | 無(wú)種屬特異性 |
應(yīng)用 | IHC-P, WB |
實(shí)驗(yàn)建議 | 最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:1000-1:2000,IHC-P:1:200-1:500。 |
克隆性 | 單克隆 |
純化工藝 | 使用表位特異性的免疫原,通過(guò)親和層析,從小鼠腹水中親和純化抗體。 |
產(chǎn)品形式 | 液體溶液 |
濃度 | 1 mg/ml |
儲(chǔ)存緩沖液 | PBS緩沖液(pH 7.4),含有0.02%疊氮化鈉(防腐劑)和50%甘油。 |
保存建議 | 自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。 |
運(yùn)輸條件 | 藍(lán)冰運(yùn)輸 |
警告 | 本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。 |
背景 | Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases , and HDACs have become promising targets for anti-cancer drugs currently in development. |
別名 | Lysine |
其它 | 該抗體可檢測(cè)內(nèi)源蛋白 |
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