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乙?;嚢彼?單克隆抗體

貨號(hào) 品牌 CAS 規(guī)格 銷售價(jià)(RMB) 折扣價(jià)(RMB) 備注 數(shù)量
ABM40200-100 μL Abbkine 無(wú) 100μL 1616 1616 無(wú)
ABM40200-30μL Abbkine 無(wú) 30μL 739 739 無(wú)
ABM40200-100μL Abbkine 無(wú) 100μL 1616 1616 無(wú)
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商品信息

產(chǎn)品英文名稱Acetyl Lysine Monoclonal Antibody
免疫原純化蛋白
宿主小鼠
反應(yīng)性無(wú)種屬特異性
應(yīng)用IHC-P, WB
實(shí)驗(yàn)建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為:WB:1:1000-1:2000,IHC-P:1:200-1:500。
克隆性單克隆
純化工藝使用表位特異性的免疫原,通過(guò)親和層析,從小鼠腹水中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
儲(chǔ)存緩沖液PBS緩沖液(pH 7.4),含有0.02%疊氮化鈉(防腐劑)和50%甘油。
保存建議自發(fā)貨之日起,-20°C可穩(wěn)定保存1年。為最大限度的避免損失,請(qǐng)?jiān)诖蜷_(kāi)管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運(yùn)輸條件藍(lán)冰運(yùn)輸
警告本文列出的產(chǎn)品僅供研究使用,不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用,不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對(duì)于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為,我們不承擔(dān)任何責(zé)任。

附加信息

背景Acetylation of lysine, like phosphorylation of serine, threonine or tyrosine, is an important reversible modification controlling protein activity. The conserved amino-terminal domains of the four core histones (H2A, H2B, H3, and H4) contain lysines that are acetylated by histone acetyltransferases (HATs) and deacetylated by histone deacetylases (HDACs). Signaling resulting in acetylation/deacetylation of histones, transcription factors, and other proteins affects a diverse array of cellular processes including chromatin structure and gene activity, cell growth, differentiation, and apoptosis. Recent proteomic surveys suggest that acetylation of lysine residues may be a widespread and important form of posttranslational protein modification that affects thousands of proteins involved in control of cell cycle and metabolism, longevity, actin polymerization, and nuclear transport. The regulation of protein acetylation status is impaired in cancer and polyglutamine diseases , and HDACs have become promising targets for anti-cancer drugs currently in development.
別名Lysine
其它該抗體可檢測(cè)內(nèi)源蛋白