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Caspase-8多克隆抗體

貨號 品牌 CAS 規(guī)格 銷售價(RMB) 折扣價(RMB) 備注 數(shù)量
ABP50858-100 μL Abbkine 無 100μL 1616 1616 無
ABP50858-30μL Abbkine 無 30μL 739 739 無
ABP50858-100μL Abbkine 無 100μL 1616 1616 無
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商品信息

產(chǎn)品英文名稱Caspase-8 Polyclonal Antibody
免疫原合成多肽：人源蛋白Caspase-8，非磷酸化多肽，中心氨基酸為S347.
宿主兔
反應(yīng)性人, 大鼠, 小鼠
應(yīng)用ELISA, IF, IHC-P, WB
實驗建議最佳的工作稀釋比例需要客戶摸索優(yōu)化。建議的起始嘗試的稀釋比為：WB：1:500-1:2000，IHC-p：1:100-1:300，ELISA：1:5000。 尚未在其他應(yīng)用中測試。
克隆性多克隆
純化工藝使用表位特異性的免疫原，通過親和層析，從兔抗血清中親和純化抗體。

商品屬性

產(chǎn)品形式液體溶液
濃度1 mg/ml
儲存緩沖液含有50％甘油，0.5％BSA和0.02％疊氮化鈉的PBS緩沖液。
保存建議自發(fā)貨之日起，-20°C可穩(wěn)定保存1年。為最大限度的避免損失，請在打開管蓋之前融化抗體并離心。我們建議使用前分裝以避免反復(fù)凍融。
運輸條件藍冰運輸
警告本文列出的產(chǎn)品僅供研究使用，不適用于人類或臨床診斷。我們產(chǎn)品所推薦應(yīng)用，不是建議使用我們的產(chǎn)品去違反任何專利或許可證。對于使用本產(chǎn)品可能發(fā)生的專利侵權(quán)或其他違規(guī)行為，我們不承擔(dān)任何責(zé)任。

附加信息

背景CASP8 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large protease subunit, and a small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This protein is involved in the programmed cell death induced by Fas and various apoptotic stimuli. The N-terminal FADD-like death effector domain of this protein suggests that it may interact with Fas-interacting protein FADD. This protein was detected in the insoluble fraction of the affected brain region from Huntington disease patients but not in those from normal controls, which implicated the role in neurodegenerative diseases. Many alternatively spliced transcript variants encoding different isoforms have been described, although not all variants have had their full-length sequences determined.
基因ID841
別名CASP8; MCH5; Caspase-8; CASP-8; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like apoptotic protease 5; MORT1-associated ced-3 homolog; MACH
其它該抗體可檢測內(nèi)源蛋白
蛋白質(zhì)IDQ14790
目標(biāo)條帶分子量（KD)55